Pharm Risk Narrative DAG CM Final - Errata 20220210

dag {
"Altered Gravity" [exposure,pos="-1.648,-0.760"]
"Antimicrobial Resistance" [pos="-1.347,-0.871"]
"Behavioral (Risk)" [latent,pos="-1.130,-1.660"]
"Bone Fracture (Risk)" [latent,pos="-1.135,-1.154"]
"Cardiovascular (Risk)" [latent,pos="-0.948,-0.970"]
"Crew Capability" [pos="-0.840,-1.599"]
"Crew Health and Performance System" [pos="-1.444,-1.596"]
"DCS (Risk)" [latent,pos="-0.900,-1.070"]
"Detect Long Term Health Outcomes" [pos="-0.728,-0.812"]
"Distance from Earth" [exposure,pos="-1.646,-1.900"]
"EVA (Risk)" [latent,pos="-0.831,-1.128"]
"Effective Mission Duration" [pos="-1.630,-1.359"]
"Electric Shock (Risk)" [latent,pos="-0.846,-1.017"]
"Fluid Shifts" [pos="-1.573,-0.842"]
"Food and Nutrition (Risk)" [latent,pos="-1.041,-0.846"]
"HSIA (Risk)" [latent,pos="-1.484,-1.783"]
"Hostile Closed Environment" [exposure,pos="-1.624,-1.212"]
"Immune (Risk)" [latent,pos="-1.135,-1.055"]
"In-Mission Shelf Life" [pos="-1.486,-1.129"]
"Individual Factors" [pos="-1.407,-0.757"]
"Individual Readiness" [pos="-0.868,-1.452"]
"Long Term Health Outcomes" [outcome,pos="-0.716,-0.995"]
"Loss of Crew Life" [outcome,pos="-0.700,-1.265"]
"Loss of Mission Objectives" [outcome,pos="-0.753,-1.838"]
"Loss of Mission" [outcome,pos="-0.708,-1.936"]
"Manufacturer Shelf Life" [pos="-1.536,-1.479"]
"Medical (Risk)" [latent,pos="-0.893,-1.290"]
"Medical Diagnostic Capability" [pos="-1.308,-0.760"]
"Medical Prevention Capability" [pos="-1.298,-0.986"]
"Medical Treatment Capability" [pos="-1.116,-1.802"]
"Medication Compatibility" [pos="-1.301,-1.685"]
"Microhost (Risk)" [latent,pos="-1.137,-0.950"]
"Pharmaceutical Effectiveness" [pos="-1.344,-1.197"]
"Pharmaceutical Storage Conditions" [pos="-1.444,-1.376"]
"Pharmaceutical Toxicity" [pos="-1.306,-1.441"]
"Radiation Carcinogenesis (Risk)" [latent,pos="-1.015,-0.719"]
"Renal Stone (Risk)" [latent,pos="-1.132,-1.352"]
"Resource Availability" [pos="-1.401,-1.893"]
"SANS (Risk)" [latent,pos="-1.179,-0.715"]
"Side Effects" [pos="-0.992,-1.743"]
"Sleep (Risk)" [latent,pos="-1.130,-1.558"]
"Suit Damage" [pos="-1.037,-1.874"]
"Suit Design" [pos="-1.268,-1.860"]
"Task Performance" [outcome,pos="-0.814,-1.732"]
"Urinary Retention (Risk)" [latent,pos="-1.135,-1.250"]
"VTE (Concern)" [latent,pos="-1.133,-1.456"]
"Vehicle Design" [pos="-1.566,-1.683"]
Absorption [pos="-1.511,-1.027"]
Distribution [pos="-1.489,-0.871"]
Elimination [pos="-1.504,-0.963"]
Evacuation [outcome,pos="-0.736,-1.513"]
Exercise [pos="-1.538,-0.741"]
Hydration [pos="-1.588,-1.004"]
Metabolism [pos="-1.468,-0.798"]
Pharmacodynamics [pos="-1.391,-1.067"]
Pharmacogenomics [pos="-1.400,-0.939"]
Pharmacokinetics [pos="-1.452,-1.024"]
Radiation [exposure,pos="-1.667,-1.072"]
Resupply [pos="-1.524,-1.889"]
Surveillance [pos="-0.860,-0.715"]
"Altered Gravity" -> "Fluid Shifts"
"Antimicrobial Resistance" -> "Pharmaceutical Effectiveness"
"Behavioral (Risk)" -> "Medical (Risk)"
"Bone Fracture (Risk)" -> "Medical (Risk)"
"Cardiovascular (Risk)" -> "Medical (Risk)"
"Crew Capability" -> "Task Performance"
"Crew Health and Performance System" -> "Medication Compatibility"
"Crew Health and Performance System" -> "Pharmaceutical Storage Conditions"
"Crew Health and Performance System" -> "Suit Design"
"DCS (Risk)" -> "Medical (Risk)"
"Distance from Earth" -> "Effective Mission Duration"
"Distance from Earth" -> "Vehicle Design"
"Distance from Earth" -> Resupply
"EVA (Risk)" -> "Medical (Risk)"
"Effective Mission Duration" -> "In-Mission Shelf Life"
"Effective Mission Duration" -> Absorption
"Electric Shock (Risk)" -> "Medical (Risk)"
"Fluid Shifts" -> Absorption
"Fluid Shifts" -> Distribution
"Fluid Shifts" -> Elimination
"Fluid Shifts" -> Metabolism
"Food and Nutrition (Risk)" -> "Medical (Risk)"
"HSIA (Risk)" -> "Crew Health and Performance System"
"HSIA (Risk)" -> "Medication Compatibility"
"HSIA (Risk)" -> "Suit Design"
"HSIA (Risk)" -> "Vehicle Design"
"Hostile Closed Environment" -> "Pharmaceutical Storage Conditions"
"Immune (Risk)" -> "Medical (Risk)"
"In-Mission Shelf Life" -> "Pharmaceutical Effectiveness"
"In-Mission Shelf Life" -> "Pharmaceutical Toxicity"
"Individual Factors" -> Absorption
"Individual Factors" -> Distribution
"Individual Factors" -> Elimination
"Individual Factors" -> Metabolism
"Individual Factors" -> Pharmacogenomics
"Individual Readiness" -> "Crew Capability"
"Long Term Health Outcomes" -> "Detect Long Term Health Outcomes"
"Loss of Mission Objectives" -> "Loss of Mission"
"Manufacturer Shelf Life" -> "In-Mission Shelf Life"
"Manufacturer Shelf Life" -> "Pharmaceutical Storage Conditions"
"Medical (Risk)" -> "Individual Readiness"
"Medical (Risk)" -> "Long Term Health Outcomes"
"Medical (Risk)" -> "Loss of Crew Life"
"Medical (Risk)" -> Evacuation
"Medical Diagnostic Capability" -> "SANS (Risk)"
"Medical Prevention Capability" -> "Behavioral (Risk)"
"Medical Prevention Capability" -> "Bone Fracture (Risk)"
"Medical Prevention Capability" -> "Food and Nutrition (Risk)"
"Medical Prevention Capability" -> "Immune (Risk)"
"Medical Prevention Capability" -> "Microhost (Risk)"
"Medical Prevention Capability" -> "Radiation Carcinogenesis (Risk)"
"Medical Prevention Capability" -> "Renal Stone (Risk)"
"Medical Prevention Capability" -> "SANS (Risk)"
"Medical Prevention Capability" -> "Side Effects"
"Medical Prevention Capability" -> "Sleep (Risk)"
"Medical Prevention Capability" -> "Urinary Retention (Risk)"
"Medical Prevention Capability" -> "VTE (Concern)"
"Medical Treatment Capability" -> "Food and Nutrition (Risk)"
"Medical Treatment Capability" -> "Medical (Risk)"
"Medical Treatment Capability" -> "Side Effects"
"Medication Compatibility" -> "Medical Treatment Capability"
"Medication Compatibility" -> "Suit Design"
"Microhost (Risk)" -> "Medical (Risk)"
"Pharmaceutical Effectiveness" -> "Medical Diagnostic Capability"
"Pharmaceutical Effectiveness" -> "Medical Prevention Capability"
"Pharmaceutical Effectiveness" -> "Medical Treatment Capability"
"Pharmaceutical Effectiveness" -> "Pharmaceutical Toxicity"
"Pharmaceutical Storage Conditions" -> "In-Mission Shelf Life"
"Pharmaceutical Toxicity" -> "Medical (Risk)"
"Radiation Carcinogenesis (Risk)" -> "Long Term Health Outcomes"
"Renal Stone (Risk)" -> "Medical (Risk)"
"Resource Availability" -> "Crew Health and Performance System"
"SANS (Risk)" -> "Medical (Risk)"
"Side Effects" -> "Individual Readiness"
"Side Effects" -> "Medical (Risk)"
"Sleep (Risk)" -> "Medical (Risk)"
"Suit Damage" -> "Loss of Mission Objectives"
"Suit Design" -> "Medical Treatment Capability"
"Suit Design" -> "Suit Damage"
"Task Performance" -> "Loss of Mission Objectives"
"Urinary Retention (Risk)" -> "Medical (Risk)"
"VTE (Concern)" -> "Medical (Risk)"
"Vehicle Design" -> "Crew Health and Performance System"
Absorption -> "Pharmaceutical Effectiveness"
Absorption -> Pharmacokinetics
Distribution -> Pharmacokinetics
Elimination -> Pharmacokinetics
Evacuation -> "Loss of Crew Life"
Evacuation -> "Loss of Mission Objectives"
Exercise -> Metabolism
Hydration -> Absorption
Hydration -> Distribution
Metabolism -> Pharmacokinetics
Pharmacodynamics -> "Pharmaceutical Effectiveness"
Pharmacogenomics -> Metabolism
Pharmacogenomics -> Pharmacodynamics
Pharmacokinetics -> Pharmacodynamics
Radiation -> "In-Mission Shelf Life"
Resupply -> "Resource Availability"
Surveillance -> "Detect Long Term Health Outcomes"
}