Bone Risk Narrative DAG CM Final Errata - 20220411

dag {
bb="0,0,1,1"
"Altered Gravity" [exposure,pos="0.054,0.304"]
"Astronaut Selection" [pos="0.052,0.743"]
"Bone Density" [pos="0.371,0.551"]
"Bone Formation" [pos="0.219,0.690"]
"Bone Fracture" [pos="0.679,0.368"]
"Bone Resorption" [pos="0.221,0.517"]
"Bone Structure" [pos="0.366,0.740"]
"Cartilage Defect" [pos="0.368,0.898"]
"Chondrocyte Metabolism" [pos="0.185,0.895"]
"Crew Capability" [pos="0.761,0.214"]
"Crew Health and Performance System" [pos="0.449,0.044"]
"DCS (Risk)" [latent,pos="0.699,0.875"]
"Detect Bone Density Changes" [pos="0.558,0.480"]
"Detect Bone Structure Changes" [pos="0.535,0.752"]
"Detect Long Term Health Outcomes" [pos="0.881,0.837"]
"Distance from Earth" [exposure,pos="0.054,0.159"]
"Dynamic Loads (Risk)" [latent,pos="0.465,0.116"]
"Endocrine Factors" [pos="0.050,0.532"]
"Flight Recertification" [outcome,pos="0.918,0.553"]
"Food and Nutrition (Risk)" [latent,pos="0.158,0.387"]
"HSIA (Risk)" [latent,pos="0.124,0.039"]
"Individual Factors" [pos="0.108,0.646"]
"Individual Readiness" [pos="0.722,0.298"]
"Long Term Health Clinical Decisions" [pos="0.729,0.754"]
"Long Term Health Outcomes" [outcome,pos="0.901,0.672"]
"Loss of Crew Life" [outcome,pos="0.919,0.446"]
"Loss of Mission Objectives" [outcome,pos="0.827,0.057"]
"Loss of Mission" [outcome,pos="0.944,0.055"]
"Medical Treatment Capability" [pos="0.676,0.041"]
"Muscle (Risk)" [latent,pos="0.398,0.294"]
"Musculoskeletal Loads" [pos="0.338,0.409"]
"Pharm (Risk)" [latent,pos="0.142,0.791"]
"Resistive Exercise" [pos="0.222,0.301"]
"Sensorimotor, Aerobic (Risks)" [latent,pos="0.425,0.205"]
"Skeletal Fragility" [pos="0.730,0.563"]
"Suit Design" [pos="0.221,0.166"]
"Task Performance" [outcome,pos="0.775,0.151"]
"Vehicle Design" [pos="0.276,0.038"]
DXA [pos="0.469,0.425"]
Evacuation [outcome,pos="0.840,0.364"]
MRI [pos="0.464,0.827"]
Osteoarthritis [pos="0.617,0.896"]
QCT [pos="0.470,0.602"]
Radiation [exposure,pos="0.050,0.889"]
Surveillance [pos="0.759,0.932"]
Ultrasound [pos="0.653,0.183"]
"Altered Gravity" -> "Chondrocyte Metabolism"
"Altered Gravity" -> "Musculoskeletal Loads"
"Astronaut Selection" -> "Individual Factors"
"Bone Density" -> "Detect Bone Density Changes"
"Bone Density" -> "Skeletal Fragility"
"Bone Formation" -> "Bone Density"
"Bone Formation" -> "Bone Structure"
"Bone Fracture" -> "Individual Readiness"
"Bone Fracture" -> "Long Term Health Outcomes"
"Bone Fracture" -> Evacuation
"Bone Fracture" -> Osteoarthritis
"Bone Resorption" -> "Bone Density"
"Bone Resorption" -> "Bone Structure"
"Bone Structure" -> "Detect Bone Structure Changes"
"Bone Structure" -> "Long Term Health Outcomes"
"Bone Structure" -> "Skeletal Fragility"
"Cartilage Defect" -> Osteoarthritis
"Chondrocyte Metabolism" -> "Cartilage Defect"
"Crew Capability" -> "Task Performance"
"Crew Health and Performance System" -> "Medical Treatment Capability"
"Crew Health and Performance System" -> "Resistive Exercise"
"Crew Health and Performance System" -> Ultrasound
"DCS (Risk)" -> "Long Term Health Outcomes"
"Detect Bone Density Changes" -> "Detect Long Term Health Outcomes"
"Detect Bone Density Changes" -> "Flight Recertification"
"Detect Bone Density Changes" -> "Long Term Health Clinical Decisions"
"Detect Bone Structure Changes" -> "Detect Long Term Health Outcomes"
"Detect Bone Structure Changes" -> "Long Term Health Clinical Decisions"
"Distance from Earth" -> "Vehicle Design"
"Dynamic Loads (Risk)" -> "Bone Fracture"
"Endocrine Factors" -> "Bone Formation"
"Endocrine Factors" -> "Bone Resorption"
"Food and Nutrition (Risk)" -> "Bone Resorption"
"HSIA (Risk)" -> "Suit Design"
"HSIA (Risk)" -> "Vehicle Design"
"Individual Factors" -> "Bone Formation"
"Individual Factors" -> "Bone Resorption"
"Individual Readiness" -> "Crew Capability"
"Long Term Health Clinical Decisions" -> "Long Term Health Outcomes"
"Long Term Health Outcomes" -> "Detect Long Term Health Outcomes"
"Loss of Mission Objectives" -> "Loss of Mission"
"Medical Treatment Capability" -> "Individual Readiness"
"Muscle (Risk)" -> "Bone Fracture"
"Muscle (Risk)" -> "Musculoskeletal Loads"
"Musculoskeletal Loads" -> "Bone Formation"
"Musculoskeletal Loads" -> "Bone Fracture"
"Musculoskeletal Loads" -> "Bone Resorption"
"Pharm (Risk)" -> "Bone Formation"
"Pharm (Risk)" -> "Bone Resorption"
"Resistive Exercise" -> "Muscle (Risk)"
"Resistive Exercise" -> "Musculoskeletal Loads"
"Sensorimotor, Aerobic (Risks)" -> "Bone Fracture"
"Skeletal Fragility" -> "Bone Fracture"
"Skeletal Fragility" -> "Long Term Health Outcomes"
"Suit Design" -> "Bone Fracture"
"Suit Design" -> "Dynamic Loads (Risk)"
"Task Performance" -> "Loss of Crew Life"
"Task Performance" -> "Loss of Mission Objectives"
"Vehicle Design" -> "Bone Fracture"
"Vehicle Design" -> "Crew Health and Performance System"
"Vehicle Design" -> "Dynamic Loads (Risk)"
DXA -> "Detect Bone Density Changes"
Evacuation -> "Loss of Crew Life"
Evacuation -> "Loss of Mission Objectives"
MRI -> "Detect Bone Structure Changes"
Osteoarthritis -> "Individual Readiness"
Osteoarthritis -> "Long Term Health Outcomes"
QCT -> "Detect Bone Density Changes"
QCT -> "Detect Bone Structure Changes"
Radiation -> "Bone Resorption"
Radiation -> "Chondrocyte Metabolism"
Surveillance -> "Detect Long Term Health Outcomes"
Ultrasound -> "Detect Bone Structure Changes"
}