OSDR Chats with Dr Jakub Mieczkowski on His Latest Publication

Welcome to OSDR Chats, a series of interviews featuring authors of OSDR-enabled publications. This format allows us to showcase key insights from researchers, offering a deeper understanding of their work while highlighting the instrumental role played by the Open Science Data Repository (OSDR) and the Analysis Working Groups (AWGs) in advancing their research. Our newest interview features the publication, “Chromosomal positioning and epigenetic architecture influence DNA methylation patterns triggered by galactic cosmic radiation” by Dr Jakub Mieczkowski at the Medical University of Gdansk in Poland.

As the field of space exploration expands, there is increasing interest in understanding the effects of cosmic radiation on human health. Cosmic radiation, such as that emitted by iron and silicon, has the potential to disrupt our DNA, resulting in changes that could affect cellular function. Dr Mieczkowski and team used eight datasets from the OSDR involving experiments on mice and analysis of astronauts, and discovered that different forms of cosmic radiation can induce varying alterations to DNA. These findings contribute valuable insights into cellular responses to space radiation, which are essential for developing strategies to safeguard the well-being of future space travelers.

OSDR recently spoke to Dr Mieczkowski to hear about the highlights of this publication and about how the Open Science data systems and Analysis Working Groups (AWGs) enabled this publication.

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