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Research Operations
& Integration

The Research Operations and Integration (ROI) element provides planning, integration, and implementation services for research tasks by NASA’s Human Research Program (HRP).

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Implementing Human Research

As an implementation arm of the Human Research Program (HRP), the ROI element coordinates the logistics of human research studies sponsored by four other HRP Elements. Click below to explore the human research aims of each.

Cross-Cutting Research Efforts

ROI supports the implementation of broad research campaigns that span HRP's elements. These include:

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Complement of Integrated Protocols for Human Research (CIPHER)

NASA astronauts are returning to the Moon with plans for one day going to Mars. To better prepare astronauts for these long journeys, scientists need to know: How do extended durations in space change the human body?

Commander Alex Gerst

Spaceflight Standard Measures

The project collects a core set measurements from astronauts throughout space station missions. This optimized, minimal set of measures is consistently captured from crewmembers to help characterize adaptive responses to and risks of living in space.

astronaut Akihiko Hoshide poses for a photo

Biological Specimen Repository

ROI has built a a storage bank to maintain biological specimens over extended periods of time and under well-controlled conditions. This repository archives blood, urine, and other biological samples for use in future spaceflight-related research.

identical twin astronauts Mark and Scott Kelly

Twins Study

What physiological, molecular, and cognitive changes could happen to a human from exposure to spaceflight? Researchers compared retired astronaut Scott Kelly while he was in space, to his identical twin brother, retired astronaut Mark Kelly, who remained on Earth.

Research on Missions that Simulate Life in Space

ROI supports the integration and implementation of human research studies within several analog missions. Click the links below to learn more.